From e06df18f87a108ed7b49a19499b97e381041899c Mon Sep 17 00:00:00 2001 From: Benito Desimone Date: Sat, 13 Sep 2025 20:38:25 +0800 Subject: [PATCH] Add 'Influence of Beta-alanine Supplementation on Skeletal Muscle Carnosine Concentrations and High Intensity Cycling Capacity' --- ...osine-Concentrations-and-High-Intensity-Cycling-Capacity.md | 3 +++ 1 file changed, 3 insertions(+) create mode 100644 Influence-of-Beta-alanine-Supplementation-on-Skeletal-Muscle-Carnosine-Concentrations-and-High-Intensity-Cycling-Capacity.md diff --git a/Influence-of-Beta-alanine-Supplementation-on-Skeletal-Muscle-Carnosine-Concentrations-and-High-Intensity-Cycling-Capacity.md b/Influence-of-Beta-alanine-Supplementation-on-Skeletal-Muscle-Carnosine-Concentrations-and-High-Intensity-Cycling-Capacity.md new file mode 100644 index 0000000..8e9d6f5 --- /dev/null +++ b/Influence-of-Beta-alanine-Supplementation-on-Skeletal-Muscle-Carnosine-Concentrations-and-High-Intensity-Cycling-Capacity.md @@ -0,0 +1,3 @@ +
Muscle carnosine synthesis is limited by the availability of beta-alanine. Thirteen male subjects were supplemented with beta-alanine (CarnoSyn) for 4 wks, 8 of these for 10 wks. A biopsy of the vastus lateralis was obtained from 6 of the 8 at 0, 4 and 10 wks. Subjects undertook a cycle capacity test to determine total work done (TWD) at 110% (CCT(110%)) of their maximum power (Wmax). Twelve matched subjects received a placebo. Eleven of these completed the CCT(110%) at 0 and 4 wks, and 8, 10 wks. Muscle biopsies were obtained from 5 of the 8 and one additional subject. 80.1% after 4 and 10 wks beta-alanine supplementation. Carnosine, initially 1.71 times higher in type IIa fibres, increased equally in both type I and IIa fibres. No increase was seen in control subjects. Taurine was unchanged by 10 wks of supplementation. 3.2% increase at 10 wks. TWD was unchanged at 4 and 10 wks in the [control subjects](https://search.yahoo.com/search?p=control%20subjects). The increase in TWD with supplementation followed the increase in muscle carnosine.
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